MtoZ Biolabs provides Comprehensive Proteomics Services powered by high-resolution mass spectrometry and fit-for-purpose workflows to support protein identification, quantification, characterization, and functional profiling across diverse biological systems. Our portfolio covers qualitative proteomics, global and targeted quantification, PTM-focused proteomics, and chemical proteomics for biomarker discovery, mechanism studies, and translational research.
What Is Proteomics Service
Proteomics Services apply analytical and quantitative strategies to measure proteins at scale, including their identities, abundances, structures, interactions, and regulatory modifications. Because proteins execute most cellular functions and respond rapidly to perturbations, proteomics data provide direct, actionable insight for biological discovery, target validation, and pathway-level understanding that complements genomics and transcriptomics.
Comprehensive Proteomics Services at MtoZ Biolabs
💠Qualitative Proteomics Services
Qualitative proteomics defines what proteins are present in a sample and supports structural, interaction, and characterization questions where confident identification is the foundation.
- Large-Scale Protein Identification Service
- Molecular Weight Determination Service
- Protein Structure Determination Service
- Protein Purity and Homogeneity Characterization Service
- Comprehensive Protein Sequencing Analysis Service
- Protein Interaction Profiling Service
💠Global Proteomic Quantification Service
Global quantitative proteomics measures proteome-wide abundance changes across conditions to reveal regulated pathways, biomarkers, and phenotype-associated protein signatures.
- DIA Quantitative Proteomics Analysis Service
- Label-free Quantitative Proteomics Analysis Service
- 4D Label-free Quantitative Proteomics Analysis Service
- TMT-based Quantitative Proteomics Analysis Service
- iTRAQ-based Quantitative Proteomics Analysis Service
- SILAC-based Quantitative Proteomics Analysis Service
💠Targeted Proteome Quantification Service
Targeted proteomics delivers high-specificity and high-sensitivity quantification of predefined protein panels for verification, validation, and focused biological questions.
- SRM/MRM Targeted Proteomics Analysis Service
- PRM Targeted Proteomics Analysis Service
- 4D-PRM Targeted Proteomics Analysis Service
- DIA+PRM Targeted Proteomics Services
- Olink Proteomics Profiling Service
- Electrochemiluminescence (ECL) Assay Service
💠Post-Translational Modification Proteome Profiling Service
PTM proteomics profiles regulatory protein modifications and their dynamics to clarify signaling, stress responses, and disease-associated regulation beyond total protein abundance.
- PTM Qualitative Analysis Service
- Quantitative PTM Omics Service
💠Chemical Proteomics Service
Chemical proteomics links small molecules to functional protein engagement and downstream biology to support target discovery, selectivity profiling, and mechanism of action.
- Activity-Based Protein Profiling (ABPP) Service
- Competitive Activity-Based Protein Profiling (ABPP) Service
- DARTS Assay Service
- Target Validation and Off-Target Analysis Service | Molecular Glue
- Target Validation and Off-Target Analysis Service | PROTAC
Workflow of Comprehensive Proteomics Services
1. Study consultation and experimental design including sample types, group layout, and quantification strategy
2. Sample preparation and QC with method selection matched to complexity and sensitivity requirements
3. LC-MS/MS data acquisition using appropriate qualitative, global quantitative, or targeted methods
4. Bioinformatics processing including identification, quantification, statistical analysis, and QC review
5. Biological interpretation with prioritized outputs for validation and follow-up experiments
6. Final report and delivery of raw and processed data
Why Choose MtoZ Biolabs
☑️Expert scientific team covering proteomics, mass spectrometry, and bioinformatics
☑️Advanced analytical platforms for sensitive, reproducible identification and quantification
☑️Modular, customizable workflows aligned to your study goals and sample constraints
☑️Efficient turnaround supported by standardized execution and clear project management
☑️Responsive customer support with practical guidance from planning through data delivery
Applications of Comprehensive Proteomics Services
1. Medicine
Comprehensive proteomics supports disease mechanism studies and biomarker discovery by profiling protein changes in tissues and biofluids.
2. Drug Development
Comprehensive proteomics enables target identification, target engagement assessment, selectivity profiling, and pathway-level readouts to guide drug discovery and development.
3. Agriculture
Proteomics analysis helps characterize proteome remodeling linked to plant growth, stress tolerance, and trait development in agricultural research.
4. Food Science
The comprehensive proteomics service supports food quality, authenticity, allergen investigation, and process-impact assessment through robust protein identification and quantification.
5. Livestock
Proteomics profiles protein signatures associated with animal health, immunity, productivity, and nutrition responses in livestock and animal science studies.
6. Environmental Science
Comprehensive proteomics reveals organismal and microbial responses to environmental stressors and supports ecosystem-level functional interpretation.
FAQ
Q1: What types of samples are suitable?
1. Biological matrices: Cell pellets, tissues, biofluids such as serum, plasma, urine, saliva, CSF, and culture supernatants.
2. Organism scope: Human and animal samples, plants, microbes, and mixed or environmental samples, depending on study goals.
3. Protein formats: Total protein lysates, enriched fractions such as subcellular organelles, purified proteins, protein complexes, and affinity-captured samples.
For unusual sample types or low-yield materials, please contact MtoZ Biolabs in advance for customized preparation guidance.
Q2: How should I prepare my samples?
1. Ensure samples are freshly prepared or snap-frozen.
2. Avoid detergents, salts, and reducing agents that may interfere with LC-MS/MS analysis.
3. Store samples at –80 °C before shipment.
4. Transport samples on dry ice to maintain stability during delivery.
Detailed requirements and recommendations can be found in the Sample Submission Guidelines for Proteomics.
Q3: What is the service general workflow?
Q4: What data formats are provided?
1. Raw data: Raw and intermediate files such as vendor raw files and search outputs can be provided upon request, based on the selected workflow.
2. Result tables: Protein identification and quantification tables delivered in CSV or Excel format, with annotations as applicable.
3. Figures: Publication-ready figures provided in PNG or TIFF format when included in the analysis package.
4. Reports: A PDF report summarizing workflow, quality control metrics, key findings, and interpretation highlights.
Additional formats can be provided upon request to meet specific analysis or publication requirements.
Start Your Project with MtoZ Biolabs
Contact us to discuss your experimental design or request a quote. Our technical specialists are available to provide a free business assessment.
